Chlormadinone acetate
Chlormadinone acetate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
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ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03A: Hormonal contraceptives for systemic use
— G03AA: Progestogens and estrogen systemic contraceptives, fixed combinations
— G03AA15: Chlormadinone and ethinylestradiol
— G03AB: Progestogens and estrogens systemic contraceptives, sequential preparations
— G03AB07: Chlormadinone and ethinylestradiol
— G03D: Progestogen sex hormones and modulators of the genital system
— G03DB: Pregnadien derivatives, progestogens
— G03DB06: Chlormadinone
— G03F: Progestogens and estrogens in combination
— G03FB: Progestogens and estrogens, sequential preparations
— G03FB03: Chlormadinone and estrogen
HCPCS
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Clinical
Clinical Trials
216 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Contraception | D003267 | — | — | 14 | 4 | 1 | 11 | 17 | 44 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | — | 12 | 4 | 1 | 2 | 17 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 3 | — | 1 | 5 | 11 |
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | 2 | 4 | 2 | 2 | 9 |
| Postmenopause | D017698 | — | — | 3 | 1 | 3 | 1 | 1 | 9 |
| Hiv | D006678 | — | O98.7 | — | 1 | — | 3 | 4 | 8 |
| Infertility | D007246 | HP_0000789 | — | — | — | 2 | 3 | 2 | 7 |
| Endometrial hyperplasia | D004714 | — | N85.0 | 1 | 4 | 2 | 2 | — | 7 |
| Osteoporosis | D010024 | HP_0000939 | M81.0 | — | — | 3 | 3 | — | 6 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | 1 | 5 | 6 |
Show 13 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Uterine hemorrhage | D014592 | — | — | 1 | 1 | 2 | — | 2 | 5 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | 3 | — | 2 | 5 |
| Coronary disease | D003327 | — | — | — | 1 | 5 | — | — | 5 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | 5 | — | — | 5 |
| Menopause | D008593 | EFO_0003922 | N95 | — | 2 | 2 | — | — | 4 |
| Healthy volunteers/patients | — | — | — | 3 | 1 | 1 | — | — | 4 |
| Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | 2 | 1 | 1 | — | — | 3 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 3 | — | — | 3 |
| Primary ovarian insufficiency | D016649 | EFO_0004266 | E28.3 | — | 1 | 1 | — | — | 2 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | 1 | — | — | 2 |
Show 17 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Endometrioid carcinoma | D018269 | — | — | — | 2 | — | — | — | 2 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 1 | — | — | — | 1 |
| Prehypertension | D058246 | — | — | — | 1 | — | — | — | 1 |
| Persistent fetal circulation syndrome | D010547 | EFO_1001103 | P29.3 | — | 1 | — | — | — | 1 |
| Myelodysplastic syndromes | D009190 | — | D46 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Contraception behavior | D003268 | — | — | 1 | — | — | — | 4 | 5 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | 2 | — | — | — | 1 | 3 |
| Postcoital contraception | D044363 | — | — | 1 | — | — | — | 1 | 2 |
| Kidney transplantation | D016030 | — | — | 1 | — | — | — | — | 1 |
| Immunosuppression therapy | D007165 | — | — | 1 | — | — | — | — | 1 |
| Pregnancy rate | D018873 | — | — | 1 | — | — | — | — | 1 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | — | — | — | — | 1 |
| Estrogen replacement therapy | D015914 | — | — | 1 | — | — | — | — | 1 |
| Postmenopausal osteoporosis | D015663 | EFO_0003854 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fertility | D005298 | — | — | — | — | — | — | 2 | 2 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
| Premenstrual dysphoric disorder | D065446 | — | F32.81 | — | — | — | — | 1 | 1 |
| Psychotic disorders | D011618 | — | F20.81 | — | — | — | — | 1 | 1 |
| Panic disorder | D016584 | EFO_0004262 | F41.0 | — | — | — | — | 1 | 1 |
| Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | — | — | — | 1 | 1 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | — | — | 1 | 1 |
| Obsessive-compulsive disorder | D009771 | EFO_0004242 | F42 | — | — | — | — | 1 | 1 |
| Social phobia | D000072861 | EFO_1001917 | F40.1 | — | — | — | — | 1 | 1 |
| Dysthymic disorder | D019263 | EFO_0008623 | F34.1 | — | — | — | — | 1 | 1 |
Show 24 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Chlormadinone acetate |
| INN | chlormadinone |
| Description | Chlormadinone acetate is a corticosteroid hormone. |
| Classification | Small molecule |
| Drug class | Progestogen; Progestin; Progestogen ester; Antigonadotropin; Steroidal antiandrogen |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C |
Identifiers
| PDB | — |
| CAS-ID | 302-22-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL110691 |
| ChEBI ID | 31394 |
| PubChem CID | 9324 |
| DrugBank | DB15903 |
| UNII ID | SDS4N642GG (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
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195 adverse events reported
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